Major research grants since 1985

Cell and Molecular Biology, Cochlear Physiology and Biophysics

Studies of hearing recovery following antibiotic damage
£130,513 to Professor Carole Hackney, University of Keele (1990/91)
Five-year project support. Grant Refs: 063, 075, 115, 116, 129, 131, 140.

Functional differentiation of mammalian cochlear hair cells in vitro
£98,646 to Dr Matthew Holley and Dr Corne Kros, University of Bristol (1999/00)
A three-year Research Fellowship awarded to Dr Richard Helyer. Supported by the Colt Foundation. Grant Ref: 259.

Mechanisms of Hair Cell Regeneration
£91,863. A three-year Deafness Research UK studentship supervised by Professor Andrew Forge and Dr Stefano Casalotti, Institute of Laryngology & Otology, UCL (1998/99). Supported by Glaxo Wellcome. Grant Ref: 273.

Measurement of mechanotransducer currents in isolated hair cells /amplification mechanisms in the inner ear
£81,550 to Professor Jonathan Ashmore and Dr Jonathan Gale, University of Bristol (1990/91). A three-year studentship and two-year Fellowship for Dr Gale. Supported by the Colt Foundation. Grant Refs: 053 and 106.

The maturation of the organ of corti in vitro and the influence of the auditory brainstem in co-culture
£75,611 to Dr Mark Souter, Institute of Laryngology & Otology, UCL (1996/97)
A two-year Deafness Research UK/Colt Foundation Research Fellowship. Grant Ref: 187.

Do hair cells arise by phenotypic conversion of supporting cells after hair cell loss in the mammalian vestibular organs?
£81,332 to Professor Andrew Forge, Institute of Laryngology & Otology, UCL (1997/98 and 2000/01)
A three-year Deafness Research UK/Mactaggart Research Fellowship awarded to Dr Victoria Camp. Grant Refs: 240 and 313.

Gap junctions in repair and recovery of sensory epithelia of the inner ear after hair cell loss
£51,032. A three-year Deafness Research UK studentship supervised by Professor Andrew Forge, Institute of Laryngology & Otology, UCL (1999/00). Grant Ref: 298.

Novel regulators of hair cell channels and applications to hearing
£53,504 to Professor Jonathan Ashmore, University College London (1995/96)
A two-year Research Fellowship for Dr Daniel Jagger. Grant Ref: 177.

Mechanical Studies of the inner ear’s tectorial membrane
£32,634. A three-year Deafness Research UK studentship supervised by Dr Nigel Cooper, University of Bristol (1997/98). Grant Ref: 217.

Ectopic Expression of Math 1 in the supporting cells of the inner ear
£44,904. A three-year postgraduate studentship supervised by Dr Guy Richardson, University of Sussex (2000/01). Grant Ref:308

Molecular and Clinical Genetics

The relative contribution of mutations in autosomal recessive DFNB genes/loci and mitochondrial DNA to congenital/childhood non-syndromal, sensorineural deafness
£316,517 to Professor Robert Mueller et al (1999/00)
A two-year project supported by the National Lottery Charities Board. Grant Ref: 278.

Mapping the gene for Treacher Collins Syndrome
£134,648 to Professor Mike Dixon, University of Manchester (1991/92)
A four-year project grant. Supported by the Independent Order of Odd Fellows. Grant Ref: 150.

A study of the clinical and molecular genetics of Waardenburg’s Syndrome Type II
£89,291 to Professor Valerie Newton and Professor Andrew Read, University of Manchester (1990/91). A three-year Clinical Research Fellowship held by Dr Xiu Zhong Liu. Grant Ref: 039.

Cloning studies of two genes for deafness in mice, Splotch and Shaker-1
£56,071 to Professor Karen Steel, MRC Institute of Hearing Research and Professor Steve Brown, St Mary’s Hospital Medical School (1990/91)
Three-year project. Grant Ref: 056.

Mutational analysis of candidate genes for Pendred Syndrome
£34,129. A three-year Deafness Research UK studentship supervised by Dr Richard Trembath, University of Leicester (1996/97). Grant Ref: 216.

Hearing aid development and central auditory processing

The Neural Basis of Sound Localisation
£109,500 to Dr Andrew King, University Laboratory of Physiology, Oxford (1997/98)
A three-year Deafness Research UK/Dunhill Medical Trust Research Fellowship awarded to Dr Jan Schnupp. Grant Ref: 215.

Perception of the pitch of complex tones by hearing-impaired people
£41,509. A three-year Deafness Research UK studentship supervised by Professor Brian Moore, University of Cambridge (1997/98). Grant Ref: 238.

Binaural processing of amplitude-modulated sounds
£41,435. A three-year Deafness Research UK studentship supervised by Dr David McAlpine, University College London (1999/00). Grant Ref: 299.

In vitro and in vivo evaluation of a one-stage earmould material
£40,604 to Dr Allison Okpojo, University of Manchester (1990/91)
An 18-month project. Grant Ref: 066.

Perceptual grouping in hearing impaired people
£37,500. A three-year Deafness Research UK studentship supervised by Professor Brian Moore, University of Cambridge (1993/94). Grant Ref:118.

Development of a wearable, fully digital hearing aid demonstrator
£32,400. A three-year Deafness Research UK studentship supervised by Professor Douglas Campbell, University of Paisley (1993/94). Grant Ref: 122.

Development of signal processing systems for separating signals from background noise
£31,409. A three-year Deafness Research UK studentship supervised by Professor Cecil Canagarajah, University of Bristol (1993/94). Grant Ref: 144.

Cochlear implants

A national evaluation of cochlear implantation in deaf children
£190,894 to Professor Quentin Summerfield, MRC Institute of Hearing Research (1997/98). A three-year project supported by the National Lottery Charities Board. Grant Ref: 188.

Clinical trial of an extra-cochlear multi-channel implant with a bioglass connector
£102,614 to Professor Tony Wright and Professor Adrian Fourcin, Institute of Laryngology and Otology, UCL (1990/91). Project support, awarded over three years. Grant Ref: 072.

The Practical Use of Additive Noise to Improve Speech Coding by Analogue Cochlear Implants
£67,123 to Dr Robert Morse, University of Keele (1998/99)
A two-year project. Grant Ref: 265.

Paediatric rehabilitation

Establishing practical and usable protocols for hearing aid fitting in babies and young children
£60,000 to Professor John Bamford, University of Manchester (1992/93)
A two-year project supported by the Clothworkers’ Foundation. Grant Ref: 094.

Screening for hearing loss

Volterra series and otoacoustic emissions
£99,392 to Dr Roger Thornton, MRC Institute of Hearing Research (1993/94)
Project funding over five years. Supported by the Colt Foundation. Grant Refs: 093; 139; 145.

Universal screening using otoacoustic emissions testing
£96,460 to Mr Colin Kennedy FRCS, University of Southampton (1990/91)
Project support over seven years. Grant Refs: 049; 172; 181.

A long-term study of the efficacy and cost-effectiveness of different neonatal screens for deafness
£35,600 to Dr John Stevens, Central Sheffield University Hospitals (1992/93)
A three-year project. Grant Ref: 097.

Otitis Media with Effusion

The expression of mucin genes in Otitis Media with effusion in children
£42,212. A three-year Deafness Research UK studentship supervised by Dr Jeff Pearson and Professor John Birchall, University of Newcastle-upon-Tyne (1994/95) Grant Refs: 133; 134.

Who are the Otitis-Prone Children (Persistent Sufferers?)
£40,000 to Professor Mark Haggard, MRC Institute of Hearing Research (1998/99)
A two-year project supported by the Clothworkers’ Foundation. Grant Ref: 260.

Tinnitus

The role of the efferent system in tinnitus
£75,276 to Mr Jonathan Hazell FRCS, The Ferens Unit, University College London (1991/92)
A three-year Research Fellowship awarded to Dr Rena Graham. Grant Refs: 075; 089.

A neuropsychological investigation of the cognitive difficulties experienced by people with tinnitus
£41,500 to Professor David Rose and Dr Richard Hallam, University of East London (1994/95). A three-year Deafness Research UK/British Tinnitus Association Postgraduate Studentship. Grant Ref: 141.

Cochlear Function in tinnitus patients undergoing Tinnitus Retraining Therapy
£34,936 to Mr Jonathan Hazell FRCS, The Ferens Unit, University College London (1995/96). A two-year project supported by the Barnwood House Trust. Grant Ref: 163.

Other research areas

Pre-operative 3D immersive surgical planning
£104,324 to Mr Ghassan Alusi FRCS, Institute of Laryngology & Otology, UCL (1995/96)
Project support over four years. Grant Ref: 194.

Deafness and dementia in elderly people
£53,764 to Professor Alistair Burns, University of Manchester (1996/97)
A two-year project supported by the Lloyds TSB Foundations. Grant Ref: 180.


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